Sugar acids and derivatives
Medchemexpress LLC NH2-C6-ARC186 sodium | 92.5% | 12,881.00 | 10 MG
NH2-C6-ARC186 sodium is an NH2-C6-modified aptamer supplied as the sodium salt that inhibits complement C5 convertase activity. The terminal aminohexyl (NH2-C6) linker enables covalent coupling to other peptides or molecules for conjugation studies. It is provided as a white to off-white solid with defined purity and molecular weight for research applications in small milligram quantities.
- Function: complement C5 convertase inhibitor
- NH2-C6 aminohexyl linker for conjugation
- Purity: 92.5%
- Physical form: white to off-white solid
- Typical sizes: 1 mg, 5 mg, 10 mg, larger sizes by quote
- Storage: in solvent -80°C (6 months) or -20°C (1 month); sealed and dry
- Molecular weight approximately 12,881 Da
Medchemexpress LLC Odn D-SL03 (sodium) | 1198621-85-0 | 98.6% | 9345 (free acid) | 10 MG
ODN D-SL03 sodium is a C-class CpG oligodeoxynucleotide TLR9 agonist supplied as a solid for research use. It stimulates peripheral blood mononuclear cells (PBMCs) to produce interferon-α, activates human B cells, NK cells, and mononuclear cells, and modulates antigen-presentation markers. The oligonucleotide sequence is 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'.
- Stimulates PBMCs to produce high levels of IFN-α.
- Activates human B cells, NK cells, and mononuclear cells.
- Up-regulates CD80, CD86, and HLA-DR expression on immune cells.
- Sequence-defined oligonucleotide: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'.
- High purity (98.6%) suitable for research applications.
- Supplied as a solid with recommended storage at -20°C; in solvent, -80°C up to 6 months.
- Available in small amounts appropriate for assays (e.g., 10 mg).
- For research use only.
Apexbio Technology LLC MG 149 1243583-85-8 25mg
MG 149 (CAS 1243583-85-8) is a small molecule inhibitor of histone acetyltransferases (HATs) exhibiting selectivity for MYST family members Tip60 and MOF with reported IC50 values of 74 M and 47 M respectively As an alkylsalicylate derivative MG 149 competitively binds to the acetyl-CoA pocket of Tip60 thereby impeding its enzymatic activity In cell-based assays using HeLa nuclear extracts MG 149 inhibited HAT activity displaying more pronounced effects on histone H3 acetylation compared to H4 Additionally transcriptomic analyses indicate that MG 149 modulates p53 and NF- B signaling pathways highlighting its utility in studying epigenetic regulation and signaling in cellular models
Medchemexpress LLC 4-methylumbelliferyl α-D-galactopyranoside | 38597-12-5 | M65400 | 99.8% | 338.31 g/mol | C16H18O8 | 25 MG
4-Methylumbelliferyl-α-D-galactopyranoside is a pro-fluorogenic substrate for α-galactosidase that releases fluorescent 4-methylumbelliferone (4-MU) upon enzymatic cleavage, enabling sensitive fluorometric detection in biochemical and enzymatic assays. Supplied as a powder with documented solubility in DMSO and defined storage conditions for stability.
- Fluorogenic substrate for α-galactosidase assays.
- Generates fluorescent 4-methylumbelliferone on enzymatic cleavage.
- High purity (99.8%) suitable for biochemical assays.
- Soluble in DMSO (≈33.3 mg/mL) for preparation of stock solutions.
- Stable when stored as powder at -20°C for long-term storage.
Medchemexpress LLC Naproxen glucuronide 1mg
Naproxen glucuronide ((S)-Naproxen- -D-glucuronide) is a non-selective COX inhibitor Naproxen glucuronide a metabolite of naproxen is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain fever swelling and stiffness[1]
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | 96.4% | 897.90 g/mol | C42H47N3O17S | 500 MG
MAC glucuronide linker-1 is a cleavable glucuronide-based linker developed for constructing antibody-drug conjugates (ADCs) in research applications. It is supplied as a solid with reported high purity and specific storage recommendations for stability.
- Cleavable glucuronide-based linker suitable for ADC construction.
- Reported purity 96.36% (typical).
- Molecular weight 897.90 g/mol.
- Chemical formula C42H47N3O17S.
- Supplied as a powder; multiple package sizes available.
- Recommended storage: 4°C under nitrogen; in solvent: -80°C (6 months), -20°C (1 month).
- For research use only; not for human therapeutic use.